Toleransen for høye doser kan avta raskt dersom man slutter med opioider eller har en pause i bruk. I slike tilfeller er male spesielt utsatt for overdoser dersom man inntar samme dose som tidligere.Behandling i spesialisthelsetjenesten krever henvisning fra lege for eksempel fastlege / allmennpraktiserende lege, privatpraktiserende legespesialist

Though there is not any proof linking the man's death to the drug, FDA officers claim that a standard physician-affected person connection, in addition to a Bodily evaluation, can have uncovered any health issues for instance heart disease and might have ensured that suitable treatment options were prescribed."This practice undermines safeguards of